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Fixed Minidose Warfarin & Aspirin Alone & in Comb vs Adjusted-Dose Warfarin for Stroke Prevent in Atrial Fib Arch Int Med 158:1513-1521, 14871998., Gullov,A.L.,et al, 1998 See this aricle in Pubmed Article Abstract Although the difference was insignificant,adjusted-dose warfarin seemed superior to minidose warfarin and to warfarin plus aspirin after 1 year of treatment.The results do not justify a change in the current recommendation of adjusted-dose warfarin(INR,2.0-3.0)for stroke prevention in atrial fibrillation.

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